Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania.

doi:10.1186/s12879-020-05491-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania.

BMC infectious diseases - 19 Oct 2020

Brown Jennifer Anne, Ringera Isaac, Luoga Ezekiel, Cheleboi Molisana, Kimera Namvua, Muhairwe Josephine, Kayembe Buntshi Paulin, Molapo Hlasoa Mosa, Kabundi Lorraine, Yav Ching Wey David, Mothobi Buoang, Thahane Lineo, Amstutz Alain, Bachmann Nadine, Mollel Getrud Joseph, Bresser Moniek, Glass Tracy Renée, Paris Daniel Henry, Klimkait Thomas, Weisser Maja, Labhardt Niklaus Daniel

Abstract excerpt

BACKGROUND: Globally, the majority of people living with HIV have no or only limited access to HIV drug resistance testing to guide the selection of antiretroviral drugs. This is of particular concern for children and adolescents, who experience high rates of treatment failure. The GIVE MOVE trial assesses the clinical impact and cost-effectiveness of routinely providing genotypic resistance testing (GRT) to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cost-Benefit Analysis

Share to Counseling

Share to Herpes Genitalis

Share to HIV

Share to Tanzania

Share to Treatment Failure

Share to Viremia

Source

Open in PubMed Open full text

Identifiers

PMID: 33076866
DOI: 10.1186/s12879-020-05491-9
PMCID: PMC7574572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania.PMID 33076866Read ↗

HIV drug resistance amongst children and adolescents with viraemia in Lesotho and Tanzania: a nested analysis in the GIVE MOVE trial.Semantic proximity Read ↗

Point-of-care HIV viral load and targeted drug resistance mutation testing versus standard care for Kenyan children on antiretroviral therapy (Opt4Kids): an open-label, randomised controlled trial.Semantic proximity Read ↗

HIV Drug Resistance Patterns and Characteristics Associated with Clinically Significant Drug Resistance among Children with Virologic Failure on Antiretroviral Treatment in Kenya: Findings from the Opt4Kids Randomized Controlled TrialSemantic proximity Read ↗

Virological outcomes and genotypic resistance on dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trialSemantic proximity Read ↗

Genotype-guided antiretroviral regimens in children with multidrug-resistant HIV-1 infection.Semantic proximity Read ↗

Factors Associated With Viral Suppression and Drug Resistance in Children and Adolescents Living With HIV in Care and Treatment Programs in Southern TanzaniaSemantic proximity Read ↗

Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2022 – cohort description, test volumes, predictors of viraemia, and the road aheadSemantic proximity Read ↗

Clinical, Psychosocial, and Structural Factors Associated with the Detection of HIV Drug Resistance in Children Living with HIV in Kisumu, Kenya: Secondary Analysis of Data from the Opt4Kids Study.Semantic proximity Read ↗

Dolutegravir-Based Therapy is Essential in Achieving HIV Epidemic Control in Low- and Middle-Income Countries: Real-Life Evidence from a Large Clinical Cohort in CameroonSemantic proximity Read ↗

Pharmaco-virological Outcomes and Genotypic Resistance Profiles Among Children and Adolescents Receiving a Dolutegravir-Based Regimen in TogoSemantic proximity Read ↗

Nucleoside reverse-transcriptase inhibitor cross-resistance and outcomes from second-line antiretroviral therapy in the public health approach: an observational analysis within the randomised, open-label, EARNEST trialSemantic proximity Read ↗

Virological impact of HIV drug-resistance testing in children, adolescents, and adults failing first-line ART in Tanzania.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.