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Article

Frailty phenotype as a predictor of bleeding and mortality in ambulatory patients receiving direct oral anticoagulants.

Journal of the American Geriatrics Society - 1 Dec 2022

Candeloro Matteo, Di Nisio Marcello, Potere Nicola, Di Pizio Lorenzo, Secinaro Enzo, De Flaviis Claudia, Federici Camilla, Guglielmi Maria Domenica, Pardi Silvana, Schulman Sam, Porreca Ettore

Abstract excerpt

BACKGROUND: Limited prospective data exist about the clinical relevance of frailty in patients with atrial fibrillation (AF) or venous thromboembolism (VTE) receiving direct oral anticoagulants (DOACs). The aim of this study was to evaluate whether frailty phenotype identifies DOAC-treated patients at higher risk of adverse clinical outcomes. METHODS: Consecutive, adult outpatients treated with DOACs for AF or...

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Identifiers

PMID: 35974661
DOI: 10.1111/jgs.18001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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