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Article

Identification of molecular subtypes, risk signature, and immune landscape mediated by necroptosis-related genes in non-small cell lung cancer

28 Jul 2022

Abstract excerpt

Background: Non-small cell lung cancer (NSCLC) is a highly heterogeneous malignancy with an extremely high mortality rate. Necroptosis is a programmed cell death mode mediated by three major mediators, RIPK1, RIPK3, and MLKL, and has been shown to play a role in various cancers. To date, the effect of necroptosis on NSCLC remains unclear. Methods: In The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus...

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PMID: 35965497
DOI: 10.3389/fonc.2022.955186

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