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Evidence of a role for cAMP in mitochondrial regulation in ovarian granulosa cells

9 Aug 2022

Abstract excerpt

In the ovary, proliferation and differentiation of granulosa cells (GCs) drive follicular growth. Our immunohistochemical study in a non-human primate, the Rhesus monkey, showed that the mitochondrial activity marker protein cytochrome c oxidase subunit 4 (COX4) increases in GCs in parallel to follicle size, and furthermore, its intracellular localization changes. This suggested that there is mitochondrial...

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PMID: 35944223
DOI: 10.1093/molehr/gaac030

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