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Article

Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus.

Molecules (Basel, Switzerland) - 8 Jul 2022

Ugbaja Samuel C, Mtambo Sphamandla E, Mushebenge Aganze G, Appiah-Kubi Patrick, Abubakar Bahijjahtu H, Ntuli Mthobisi L, Kumalo Hezekiel M

Abstract excerpt

The use of vaccinations and antiviral medications have gained popularity in the therapeutic management of avian influenza H7N9 virus lately. Antiviral medicines are more popular due to being readily available. The presence of the neuraminidase protein in the avian influenza H7N9 virus and its critical role in the cleavage of sialic acid have made it a target drug in the development of influenza virus drugs....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35889251
DOI: 10.3390/molecules27144376
PMCID: PMC9317591

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Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus.PMID 35889251Read ↗

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