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Article

Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis.

Journal of gastroenterology - 1 Oct 2022

Wang Ziyu, Iida Noriho, Seishima Jun, Okafuji Hirofumi, Yutani Masahiro, Fujinaga Yukako, Hashimoto Yusuke, Tomita Haruyoshi, Mizukoshi Eishiro, Kaneko Shuichi

Abstract excerpt

BACKGROUND: Dysbiosis of gut microbiota promotes colitis in ulcerative colitis (UC). Enterococcus faecium is an important constituent of dysbiotic microbiota. However, the mechanisms underlying E. faecium-induced colitis remain unclear. METHODS: Overall, 23 E. faecium strains isolated from human feces and 3 commercial strains were inoculated into Il10-/- mice. Mouse colons were histologically evaluated and...

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Identifiers

PMID: 35882645
DOI: 10.1007/s00535-022-01905-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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