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IL22RA1/JAK/STAT Signaling Acts As a Cancer Target Through Pan-Cancer Analysis

8 Jul 2022

Abstract excerpt

Cytokines and cytokine receptors are important mediators in immunity and cancer development. Interleukin 22 (IL22) is one of the most important cytokines which has protumor effect. Given that common and specific roles of cytokines/receptors in multiple cancers, we conducted a pan-cancer study to investigate the role of IL22RA1 in cancer using The Cancer Genome Atlas (TCGA) database. Notably, we found IL22RA1...

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PMID: 35874683
DOI: 10.3389/fimmu.2022.915246

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