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Article

Rotavirus vaccine-derived cases in Belgium: Evidence for reversion of attenuating mutations and alternative causes of gastroenteritis.

Vaccine - 19 Aug 2022

Simsek Ceren, Bloemen Mandy, Jansen Daan, Descheemaeker Patrick, Reynders Marijke, Van Ranst Marc, Matthijnssens Jelle

Abstract excerpt

Since the introduction of live-attenuated rotavirus vaccines in Belgium in 2006, surveillance has routinely detected rotavirus vaccine-derived strains. However, their genomic landscape and potential role in gastroenteritis have not been thoroughly investigated. We compared VP7 and VP4 nucleotide sequences obtained from rotavirus surveillance with the Rotarix vaccine sequence. As a result, we identified 80...

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Identifiers

PMID: 35871871
DOI: 10.1016/j.vaccine.2022.06.082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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