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Rotavirus genotypes and clinical outcome of natural infection based on vaccination status in the post-vaccine era.

Human vaccines & immunotherapeutics - 31 Dec 2022

Kozawa Kei, Higashimoto Yuki, Kawamura Yoshiki, Miura Hiroki, Negishi Takumi, Hattori Fumihiko, Ihira Masaru, Komoto Satoshi, Taniguchi Koki, Yoshikawa Tetsushi

Abstract excerpt

Rotavirus (RV) is a leading cause of gastroenteritis in children. In Japan, Rotarix (RV1; GlaxoSmithKline), which is a monovalent vaccine derived from human RV (G1P[8]), has been introduced since November 2011, and RotaTeq (RV5; MSD) which is an pentavalent, human-bovine mono-reassortant vaccine (G1, G2, G3, G4, and P1A[8]), has been introduced since July 2012. Long-term follow-up on vaccine efficacy and RV...

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Identifiers

PMID: 35240934
DOI: 10.1080/21645515.2022.2037983
PMCID: PMC9009920

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