Article
The mutation features and geographical distributions of the surface glycoprotein (S gene) in SARS-CoV-2 strains: A comparative analysis of the early and current strains.
Journal of medical virology - 1 Nov 2022
Liu Rang, Lin Xinran, Chen Bing, Hou Zhenhui, Zhang Qiuju, Lin Shouren, Geng Lan, Sun Zhongyi, Cao Canhui, Shi Yu, Xia Xi
Abstract excerpt
The surface glycoprotein (S protein) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was used to develop coronavirus disease 2019 (COVID-19) vaccines. However, SARS-CoV-2, especially the S protein, has undergone rapid evolution and mutation, which has remained to be determined. Here, we analyzed and compared the early (12 237) and the current (more than 10 million) SARS-CoV-2 strains to identify...
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