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COVID-19: Challenges of Viral Variants

18 Jul 2022

Abstract excerpt

The COVID-19 pandemic has been accompanied by SARS-CoV-2 evolution and emergence of viral variants that have far exceeded initial expectations. Five major variants of concern (Alpha, Beta, Gamma, Delta, and Omicron) have emerged, each having both unique and overlapping amino acid substitutions that have affected transmissibility, disease severity, and susceptibility to natural or vaccine-induced immune responses...

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PMID: 35850493
DOI: 10.1146/annurev-med-042921-020956

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