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Article

Fibroblast morphology, growth rate and gene expression in facial melasma

12 Jul 2022

Abstract excerpt

BACKGROUND: In addition to melanocytic hyperfunction, changes are observed in the upper dermis of melasma, and fibroblasts play a central role in collagen synthesis and pigmentation induction. OBJECTIVE: To explore the morphology, growth rate, and gene expression profile of fibroblasts from the skin with melasma in comparison to fibroblasts from the adjacent healthy skin. METHODS: Ten women with facial melasma...

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PMID: 35840442
DOI: 10.1016/j.abd.2021.09.012

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