Lactobacillus plantarum Combined with Galactooligosaccharides Supplement: A Neuroprotective Regimen Against Neurodegeneration and Memory Impairment by Regulating Short-Chain Fatty Acids and the c-Jun N-Terminal Kinase Signaling Pathway in Mice

Abstract excerpt

Probiotics and prebiotics have received attention in alleviating neurodegenerative diseases. Lactobacillus plantarum ( L. plantarum ) 69-2 was combined with galactooligosaccharides (GOS) and supplemented in a d -galactose ( d -gal)-induced neurodegeneration and memory impairment mice model to explore its effects on the brain and the regulation of short-chain fatty acids. The results showed that the L. plantarum...

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