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Article

Caspases in developmental cell death.

IUBMB life - 1 Aug 1999

Shearwin-Whyatt L M, Kumar S

Abstract excerpt

Caspases are a family of evolutionarily conserved cysteine proteases that constitute the effector arm of the apoptotic machinery. Studies in Caenorhabditis elegans, Drosophila melanogaster, and mouse point to evolutionarily conserved caspase function in developmentally programmed cell death in metazoans. Whereas in the nematode all developmental cell death is mediated by a single caspase, in Drosophila and the...

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PMID: 10794589
DOI: 10.1080/713803494

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