Article
Comparison of the somatic mutations between circulating tumor DNA and tissue DNA in Chinese patients with non-small cell lung cancer.
The International journal of biological markers - 1 Dec 2022
Zhang Meng, Feng Yi, Qu Changda, Meng Meizhu, Li Wenmei, Ye Meiying, Li Sisi, Li Shaolei, Ma Yuanyuan, Wu Nan, Jia Shuqin
Abstract excerpt
BACKGROUND: Non-invasive liquid biopsies of circulating tumor DNA (ctDNA) is a rapidly growing field in the research of non-small cell lung cancer (NSCLC). In this study, factors affecting the concordance of mutations in paired plasma and tissue and the detection rate of ctDNA in real-world Chinese patients with NSCLC were identified. METHODS: Peripheral blood and paired formalin-fixed paraffin-embedded tumor...
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