Article
HIV-1 Subtype Shift in the Philippines is Associated With High Transmitted Drug Resistance, High Viral Loads, and Fast Immunologic Decline.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2022
Salvaña Edsel Maurice T, Dungca Niña Theresa, Arevalo Geraldine, Li Kingbherly, Francisco Christian, Penalosa Christine, Dela Tonga Angelo, Leyritana Katerina, Solante Rontgene, Tactacan-Abrenica Rosario Jessica, Lim Jodor, Alejandria Marissa, Palaypayon Noel, Schwem Brian
Abstract excerpt
OBJECTIVES: The Philippines has one of the fastest growing HIV epidemics in the world. A subtype shift from B to CRF01_AE may have contributed to the increase in cases. We undertook a genotyping and transmitted drug resistance (TDR) study to determine if the dominant subtype has any advantages in resistance and transmission. METHODS: Filipinos who were treatment-naive who were living with HIV were recruited from...
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