Association between matrix metalloproteinase-9 gene polymorphism and breast cancer in Brazilian women.

doi:10.6061/clinics/2020/e1762

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Association between matrix metalloproteinase-9 gene polymorphism and breast cancer in Brazilian women.

Clinics (Sao Paulo, Brazil) - 1 Jan 2020

Oliveira Victor Alves de, Chagas Diego Cipriano, Amorim Jefferson Rodrigues, Pereira Renato de Oliveira, Nogueira Thais Alves, Borges Victória Maria Luz, Campos-Verde Larysse Maira, Martins Luana Mota, Rodrigues Gilmara Peres, Nery Júnior Elmo de Jesus, Sampaio Fabiane Araújo, Lopes-Costa Pedro Vitor, Sousa João Marcelo de Castro E, Silva Vladmir Costa, Silva Felipe Cavalcanti Carneiro da, Silva Benedito Borges da

Abstract excerpt

OBJECTIVE: This study aimed to determine the relationship between rs17576 (MMP-9) polymorphism and increased cancer risk in a Brazilian breast cancer cohort. METHODS: This study included 141 women (71 breast cancer patients and 70 controls without breast cancer) who donated 3 mL of their peripheral blood for genomic DNA extraction. This DNA was then genotyped using a real-time polymerase chain reaction. RESULTS:...

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Identifiers

PMID: 33146350
DOI: 10.6061/clinics/2020/e1762
PMCID: PMC7561070

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