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Chest computed tomography improvement in patients with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: Early report.

European journal of radiology - 1 Sept 2022

Bec Romain, Reynaud-Gaubert Martine, Arnaud François, Naud Romain, Dufeu Nadine, Di Bisceglie Mathieu, Coiffard Benjamin, Gaubert Jean-Yves, Bermudez Julien, Habert Paul

Abstract excerpt

RATIONALE AND OBJECTIVES: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have revolutionised the treatment of cystic fibrosis (CF). Chest computed tomography (CT) is key in the diagnosis and follow-up of anatomical damage to the lungs. Our study aimed to evaluate changes on lung CT scans of patients with CF after receiving elexacaftor-tezacaftor-ivacaftor (ETI) therapy for one year....

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Identifiers

PMID: 35772339
DOI: 10.1016/j.ejrad.2022.110421

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