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Article

A Novel Role of IL13Rα2 in the Pathogenesis of Proliferative Vitreoretinopathy

13 Jun 2022

Abstract excerpt

Proliferative vitreoretinopathy (PVR), an inflammatory and fibrotic blinding disease, is still a therapeutic challenge. Retinal pigment epithelial (RPE) cells dislodged in the vitreous play a central role in the PVR pathogenesis. To identify potential novel contributors to the pathogenesis of PVR, we investigated a profile of vitreous-induced changes in ARPE-19 cells by RNA sequencing. Bioinformatics analysis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35770008
DOI: 10.3389/fmed.2022.831436

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