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Comprehensive analysis of prognostic tumor microenvironment-related genes in osteosarcoma patients

27 Aug 2020

Abstract excerpt

BACKGROUND: Tumor microenvironment (TME) plays an important role in malignant tumors. Our study aimed to investigate the effect of the TME and related genes in osteosarcoma patients. METHODS: Gene expression profiles and clinical data of osteosarcoma patients were downloaded from the TARGET dataset. ESTIMATE algorithm was used to quantify the immune score. Then, the association between immune score and prognosis...

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PMID: 32854645
DOI: 10.1186/s12885-020-07216-2

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