Germline landscape of BRCAs by 7-site collaborations as a BRCA consortium in Turkey.

doi:10.1016/j.breast.2022.06.005

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Germline landscape of BRCAs by 7-site collaborations as a BRCA consortium in Turkey.

Breast (Edinburgh, Scotland) - 1 Oct 2022

Bisgin Atil, Sag Sebnem Ozemri, Dogan Muhammet E, Yildirim Mahmut S, Gumus Aydeniz Aydin, Akkus Nejmiye, Balasar Ozgur, Durmaz Ceren D, Eroz Recep, Altiner Sule, Alemdar Adem, Aliyeva Lamia, Boga Ibrahim, Cam Fethi S, Dogan Berkcan, Esbah Onur, Hanta Abdullah, Mujde Cem, Ornek Cemre, Ozer Sinem, Rencuzogullari Cagla, Sonmezler Ozge, Bozdogan Sevcan Tug, Dundar Munis, Temel Sehime G

Abstract excerpt

BRCA1/2 mutations play a significant role in cancer pathogenesis and predisposition particularly in breast, ovarian and prostate cancers. Thus, germline analysis of BRCA1 and BRCA2 is essential for clinical management strategies aiming at the identification of recurrent and novel mutations that could be used as a first screening approach. We analyzed germline variants of BRCA1/2 genes for 2168 individuals who had...

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Identifiers

PMID: 35753294
DOI: 10.1016/j.breast.2022.06.005
PMCID: PMC9249944

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