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Article

Macrophage‐specific FGF12 promotes liver fibrosis progression in mice

26 Jun 2022

Abstract excerpt

BACKGROUND AND AIMS: Chronic liver diseases are associated with the development of liver fibrosis. Without treatment, liver fibrosis commonly leads to cirrhosis and HCC. FGF12 is an intracrine factor belonging to the FGF superfamily, but its role in liver homeostasis is largely unknown. This study aimed to investigate the role of FGF12 in the regulation of liver fibrosis. APPROACH AND RESULTS: FGF12 was...

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PMID: 35753047
DOI: 10.1002/hep.32640

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