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Molecular and cellular pathways in colorectal cancer: apoptosis, autophagy and inflammation as key players

22 Jun 2022

Abstract excerpt

BACKGROUND: Colorectal carcinogenesis (CRC) is one of the most aggressive forms of cancer, particularly in developing countries. It accounts for the second and third-highest reason for cancer-induced lethality in women and men respectively. CRC involves genetic and epigenetic modifications in colonic epithelium, leading to colon adenocarcinoma. The current review highlights the pathogenic mechanisms and...

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PMID: 35732586
DOI: 10.1080/00365521.2022.2088247

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