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The role of autophagy in colitis-associated colorectal cancer

28 Nov 2018

Abstract excerpt

Autophagy is an evolutionarily conserved catabolic process that eliminates harmful components through lysosomal degradation. In addition to its role in maintaining cellular homeostasis, autophagy is critical to pathological processes, such as inflammation and cancer. Colitis-associated colorectal cancer (CAC) is a specific type of colorectal cancer that develops from long-standing colitis in inflammatory bowel...

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PMID: 30510778
DOI: 10.1038/s41392-018-0031-8

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