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Vision-related convergent gene losses reveal SERPINE3’s unknown role in the eye

21 Jun 2022

Abstract excerpt

Despite decades of research, knowledge about the genes that are important for development and function of the mammalian eye and are involved in human eye disorders remains incomplete. During mammalian evolution, mammals that naturally exhibit poor vision or regressive eye phenotypes have independently lost many eye-related genes. This provides an opportunity to predict novel eye-related genes based on specific...

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PMID: 35727138
DOI: 10.7554/elife.77999

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