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Article

Decreased CD11c-positive dendritic cells in the tumor microenvironment predict double-hit/triple-hit genotype and survival in diffuse large B-cell lymphoma.

The journal of pathology. Clinical research - 1 Sept 2022

Yuan Chang-Tsu, Chuang Shih-Sung, Cheng Pei-Yuan, Chang Koping, Wang Hsuan, Tsai Jia-Huei, Liau Jau-Yu, Chou Wen-Chien

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and is a potentially curable disease. However, it is heterogenous, and the prognosis is poor if the tumor cells harbor fusions involving MYC and BCL2 or MYC and BCL6 (double-hit [DH] lymphoma), or fusions involving all three genes (triple-hit [TH] lymphoma). Fluorescence in situ hybridization is currently the gold standard for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-bcl-2

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Identifiers

PMID: 35715938
DOI: 10.1002/cjp2.283
PMCID: PMC9353657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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