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Article

Molecular characterization of emerging variants of PRRSV in the United States: new features of the -2/-1 programmed ribosomal frameshifting signal in the nsp2 region.

Virology - 1 Aug 2022

Yan Xingyu, Shang Pengcheng, Yim-Im Wannarat, Sun Yankuo, Zhang Jianqiang, Firth Andrew E, Lowe James F, Fang Ying

Abstract excerpt

In this study, we characterized an emerging porcine reproductive and respiratory syndrome virus (PRRSV) isolate UIL21-0712, which is a lineage 1C variant with ORF5 restriction fragment length polymorphism (RFLP) cutting pattern of 1-4-4. The UIL21-0712 genome sequence has 85.3% nucleotide identity with the prototypic PRRSV-2 strain VR2332. The nsp2 region is the most variable, and the -2/-1 programmed ribosome...

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Identifiers

PMID: 35714457
DOI: 10.1016/j.virol.2022.06.004
PMCID: PMC7618843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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