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Article

Genetically predicted higher educational attainment decreases the risk of stroke: a multivariable Mendelian randomization study.

BMC cardiovascular disorders - 16 Jun 2022

Zhang Weihao, Li Yuanjin, Li Yuming, Zheng Kai, Zou Shenghui, Jia Xing, Yang Hua

Abstract excerpt

BACKGROUND: The causal association between educational attainment (EA) and stroke remains unclear. Hence, a novel multivariable Mendelian randomization (MVMR) approach was applied to solve this issue. METHODS: The single nucleotide polymorphisms (SNPs) from a recent genome-wide association study (GWAS) on years of schooling served as instruments. Univariable mendelian randomization (MR) and MVMR analyses were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35710362
DOI: 10.1186/s12872-022-02713-7
PMCID: PMC9205080

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