Article
Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome.
Haematologica - 1 Jan 2023
Veloza Luis, Cavalieri Doriane, Missiaglia Edoardo, Ledoux-Pilon Albane, Bisig Bettina, Pereira Bruno, Bonnet Christophe, Poullot Elsa, Quintanilla-Martinez Leticia, Dubois Romain, Llamas-Gutierrez Francisco, Bossard Céline, De Wind Roland, Drieux Fanny, Fontaine Juliette, Parrens Marie, Sandrini Jeremy, Fataccioli Virginie, Delfau-Larue Marie-Hélène, Daniel Adrien, Lhomme Faustine, Clément-Filliatre Lauriane, Lemonnier François, Cairoli Anne, Morel Pierre, Glaisner Sylvie, Joly Bertrand, El Yamani Abderrazak, Laribi Kamel, Bachy Emmanuel, Siebert Reiner, Vallois David, Gaulard Philippe, Tournilhac Olivier, De Leval Laurence
Abstract excerpt
Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare aggressive T-cell lymphoma most reported in Asia. We performed a comprehensive clinical, pathological and genomic study of 71 European MEITL patients (36 males, 35 females, median age 67 years). The majority presented with gastrointestinal involvement and had emergency surgery, and 40% had stage IV disease. The tumors were morphologically...
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