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The Awesome Power of Human Genetics of Infectious Disease

13 Jun 2022

Abstract excerpt

Since the identification of sickle cell trait as a heritable form of resistance to malaria, candidate gene studies, linkage analysis paired with sequencing, and genome-wide association (GWA) studies have revealed many examples of genetic resistance and susceptibility to infectious diseases. GWA studies enabled the identification of many common variants associated with small shifts in susceptibility to infectious...

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PMID: 35697043
DOI: 10.1146/annurev-genet-080320-010449

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