Article
Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better?
The Lancet. Infectious diseases - 1 Oct 2006
Burgner David, Jamieson Sarra E, Blackwell Jenefer M
Abstract excerpt
Genetic epidemiology, including twin studies, provides robust evidence that genetic variation in human populations contributes to susceptibility to infectious disease. One of the major limitations of studies that attempt to identify the genes and mechanisms that underlie this susceptibility has been lack of power caused by small sample size. With the development of novel technologies, burgeoning information on...
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