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Mendel's First Law: partisan interests and the parliament of genes.

Heredity - 1 Jul 2022

Veller Carl

Abstract excerpt

Mendel's First Law requires explanation because of the possibility of 'meiotic drivers', genes that distort fair segregation for selfish gain. The suppression of drive, and the restoration of fair segregation, is often attributed to genes at loci unlinked to the drive locus-such genes cannot benefit from drive but do suffer its associated fitness costs. However, selection can also favour suppressors at loci...

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PMID: 35690638
DOI: 10.1038/s41437-022-00545-x
PMCID: PMC9273594

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