Article
An Active Learning Framework Improves Tumor Variant Interpretation.
Cancer research - 3 Aug 2022
Blee Alexandra M, Li Bian, Pecen Turner, Meiler Jens, Nagel Zachary D, Capra John A, Chazin Walter J
Abstract excerpt
SIGNIFICANCE: A novel machine learning approach predicts the impact of tumor mutations on cellular phenotypes, overcomes limited training data, minimizes costly functional validation, and advances efforts to implement cancer precision medicine.
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