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Development of a Topical Bacteriophage Gel Targeting <i>Cutibacterium Acnes</i> for Acne Prone Skin and Results of a Phase 1 Cosmetic Randomized Clinical Trial

28 Jan 2022

Abstract excerpt

Abstract Background Topical antibiotics are frequently used to treat acne vulgaris. Their prolonged use, often for longer durations than recommended, has led to antibiotic resistance in Cutibacterium acnes (C. acnes), a bacterium implicated in acne pathophysiology. Bacteriophage (phage), which specifically target C. acnes by a different mechanism of action and do not harm potentially beneficial bacteria, may...

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PMID: 35677920
DOI: 10.1002/ski2.93

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