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Article

Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates.

mBio - 1 Jan 2012

Marinelli Laura J, Fitz-Gibbon Sorel, Hayes Clarmyra, Bowman Charles, Inkeles Megan, Loncaric Anya, Russell Daniel A, Jacobs-Sera Deborah, Cokus Shawn, Pellegrini Matteo, Kim Jenny, Miller Jeff F, Hatfull Graham F, Modlin Robert L

Abstract excerpt

UNLABELLED: Investigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial inhabitant, Propionibacterium acnes, which is thought to contribute to the pathogenesis of the human disease acne. To explore the diversity of the bacteriophages that...

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PMID: 23015740
DOI: 10.1128/mBio.00279-12
PMCID: PMC3448167

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