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Article

Cleidocranial dysplasia and novel RUNX2 variants: dental, craniofacial, and osseous manifestations.

Journal of applied oral science : revista FOB - 1 Jan 2022

Thaweesapphithak Sermporn, Saengsin Jirawat, Kamolvisit Wuttichart, Theerapanon Thanakorn, Porntaveetus Thantrira, Shotelersuk Vorasuk

Abstract excerpt

OBJECTIVES: Cleidocranial dysplasia (CCD) is a skeletal disorder affecting cranial sutures, teeth, and clavicles, and is associated with the RUNX2 mutations. Although numerous patients have been described, a direct genotype-phenotype correlation for RUNX2 has been difficult to establish. Further cases must be studied to understand the clinical and genetic spectra of CCD. To characterize detailed phenotypes and...

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PMID: 35674542
DOI: 10.1590/1678-7757-2022-0028
PMCID: PMC9239300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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