Article
Sensitivity analysis of EGFR L861Q mutation to six tyrosine kinase inhibitors.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Oct 2022
Liu Chang, Wang Zhenxing, Liu Qian, Wu Guangyao, Chu Chunhong, Li Lanxin, An Lei, Duan Shaofeng
Abstract excerpt
PURPOSE: Lung cancer is one of the most common carcinomas with the highest mortality in the world. Non-small cell lung carcinoma has a large proportion of epidermal growth factor receptor (EGFR) mutations, of which rare EGFR mutations account for about 10%-20%. Currently, tyrosine kinase inhibitors (TKIs) therapy is a standard treatment for patients with non-small cell lung carcinoma with EGFR mutations. To date,...
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