Article
Molecular Characterization and Phylogenetic Analysis of the 2019 Dengue Outbreak in Wenzhou, China.
Frontiers in cellular and infection microbiology - 1 Jan 2022
Han Axiang, Sun Baochang, Sun Zhewei, Xu Xuelian, Yang Qiongying, Xie Danli, Guan Wanchun, Lou Yongliang
Abstract excerpt
In 2019, a dengue outbreak occurred with 290 confirmed cases in Wenzhou, a coastal city in southeast China. To identify the origin of the dengue virus (DENV) from this outbreak, viral RNA was extracted from four serum samples and sequenced for whole genome analysis. Then, phylogenetic analysis, gene mutation, secondary structure prediction, selection pressure analysis, and recombination analysis were performed....
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