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Article

Asp50Glu mutation in MurA results in fosfomycin resistance in Enterococcus faecium.

Journal of global antimicrobial resistance - 1 Sept 2022

Xin Ling, Hu Zetao, Han Renru, Xu Xiaogang, Wang Chuning, Li Dan, Guo Yan, Hu Fupin

Abstract excerpt

OBJECTIVES: Enterococcus faecium is one of the important pathogens causing nosocomial infection, which can be resistant to fosfomycin by obtaining the plasmid-encoded fosfomycin resistance genes, and the mutation of MurA protein encoded by chromosome is a newly discovered fosfomycin resistance mechanism in recent years. METHODS: In this study, we found a fosfomycin-resistant clinical isolate of E. faecium...

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Identifiers

PMID: 35660662
DOI: 10.1016/j.jgar.2022.05.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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