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Article

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

21 Jan 2019

Abstract excerpt

Cranial growth and development is a complex process which affects the closely related traits of head circumference (HC) and intracranial volume (ICV). The underlying genetic influences shaping these traits during the transition from childhood to adulthood are little understood, but might include both age-specific genetic factors and low-frequency genetic variation. Here, we model the developmental genetic...

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PMID: 30664637
DOI: 10.1038/s41467-018-07863-x

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