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Article

HLA analysis of immune checkpoint inhibitor-induced and idiopathic isolated ACTH deficiency.

Pituitary - 1 Aug 2022

Ono Mayo, Fukuda Izumi, Nagao Mototsugu, Tomiyama Keiko, Okazaki-Hada Mikiko, Shuto Yuki, Kobayashi Shunsuke, Yamaguchi Yuji, Nagamine Tomoko, Nakajima Yasushi, Inagaki-Tanimura Kyoko, Sugihara Hitoshi

Abstract excerpt

PURPOSE: Isolated adrenocorticotropic hormone deficiency is a rare disease; however, since immune check point inhibitors (ICIs) have become widely used, many more cases have been reported. In this study, we compared the human leukocyte antigen (HLA) signatures between ICI-induced isolated adrenocorticotropic hormone deficiency (IAD) and idiopathic IAD (IIAD). DESIGN AND METHODS: Clinical features and HLA...

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Identifiers

PMID: 35653047
DOI: 10.1007/s11102-022-01231-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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