Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of neuropathology in the management of progressive glioblastoma in adults.

Abstract excerpt

TARGET POPULATION: These recommendations apply to adult patients with progressive or recurrent glioblastoma (GBM). QUESTION: For adult patients with progressive glioblastoma does testing for Isocitrate Dehydrogenase (IDH) 1 or 2 mutations provide new additional management or prognostic information beyond that derived from the tumor at initial presentation? RECOMMENDATION: Level III: Repeat IDH mutation testing is...

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