[Smith-Lemli-Opitz syndrome: evaluation of the correlations between individual traits as an approach to the study of heterogeneity].

Article

[Smith-Lemli-Opitz syndrome: evaluation of the correlations between individual traits as an approach to the study of heterogeneity].

TSitologiia i genetika - 1 Jan 2000

Nikonovich Iu B, Kaurov B A, Lur'e I V

Abstract excerpt

A computer analysis was used to study heterogeneity of the Smith-Lemli-Opitz syndrome (SLOS) with or without certain anomalies and to determine intrafamilial phenotypical variability. The analysis of 83 SLOS cases showed significant differences in average values of intragroup similarity, estimate...

Topics

Abnormalities, Multiple
Alleles
Cleft Palate
Fingers
Genetic Variation
Humans
Phenotype
Syndrome
Toes

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