Article
transferGWAS: GWAS of images using deep transfer learning.
Bioinformatics (Oxford, England) - 11 Jul 2022
Kirchler Matthias, Konigorski Stefan, Norden Matthias, Meltendorf Christian, Kloft Marius, Schurmann Claudia, Lippert Christoph
Abstract excerpt
MOTIVATION: Medical images can provide rich information about diseases and their biology. However, investigating their association with genetic variation requires non-standard methods. We propose transferGWAS, a novel approach to perform genome-wide association studies directly on full medical images. First, we learn semantically meaningful representations of the images based on a transfer learning task, during...
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