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Article

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls-The GEA Mexican Study.

Biomolecules - 19 Apr 2022

Vargas-Alarcón Gilberto, Fragoso José Manuel, Ramírez-Bello Julian, Posadas-Sánchez Rosalinda

Abstract excerpt

FOXA3 is a transcription factor involved in the macrophage cholesterol efflux and macrophage reverse cholesterol transport reducing the atherosclerotic lesions. Thus, the present study aimed to establish if the FOXA3 polymorphisms are associated with subclinical atherosclerosis (SA) and cardiometabolic parameters. Two FOXA3 polymorphisms (rs10410870 and rs10412574) were determined in 386 individuals with SA and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35625529
DOI: 10.3390/biom12050601
PMCID: PMC9139129

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