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Discovering Biological Conflict Systems Through Genome Analysis: Evolutionary Principles and Biochemical Novelty

24 May 2022

Abstract excerpt

Biological replicators, from genes within a genome to whole organisms, are locked in conflicts. Comparative genomics has revealed a staggering diversity of molecular armaments and mechanisms regulating their deployment, collectively termed biological conflict systems. These encompass toxins used in inter- and intraspecific interactions, self/nonself discrimination, antiviral immune mechanisms, and counter-host...

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PMID: 35609893
DOI: 10.1146/annurev-biodatasci-122220-101119

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