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Relation between mutations in the 5' UTR of ANKRD26 gene and inherited thrombocytopenia with predisposition to myeloid malignancies. An Egyptian study.

Platelets - 4 Jul 2021

Zidan Nahla Ibrahim, AbdElmonem Doaa Metwally, Elsheikh Haitham Mohamed, Metwally Elsayed Anany, Mokhtar Wesam AbdElmonem, Osman Gamal Mohamed

Abstract excerpt

Inherited thrombocytopenias are a heterogeneous group of diseases characterized by a reduced number of platelets and a bleeding tendency that ranges from very mild to life threatening especially in surgery. Mutations in the 5' untranslated region (UTR) of Ankirin repeat domain 26 (ANKRD26) are responsible for autosomal-dominant form of thrombocytopenia, that is known as ANKRD26-related thrombocytopenia (ANKRD26...

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PMID: 32659145
DOI: 10.1080/09537104.2020.1790512

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Relation between mutations in the 5' UTR of ANKRD26 gene and inherited thrombocytopenia with predisposition to myeloid malignancies. An Egyptian study.PMID 32659145Read ↗

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