Article
Lipid Metabolic Genes and Maternal Supraphysiological Hypercholesterolemia: An Analysis of Maternal-fetal Interaction.
The Journal of clinical endocrinology and metabolism - 14 Jul 2022
Cai Xiaxia, Liang Ning, Cai Xueping, Zhou Qi, Dang Qinyu, Hu Zhuo, Yu Huanling
Abstract excerpt
CONTEXT: The joint associations of maternal and fetal single nucleotide polymorphisms (SNPs) of lipid metabolic genes with the risk of maternal supraphysiological hypercholesterolemia (MSPH) are unclear. OBJECTIVE: This study aims to investigate the associations of maternal/fetal SNPs of APOE, LPL, LDLR, PCSK9, and SCARB1 with the risk of MSPH and explore whether the maternal-fetal pairing pattern of the risk...
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