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NPAS4 Polymorphisms Contribute to Coronary Heart Disease (CHD) Risk.

Cardiovascular toxicology - 1 Jun 2022

Yan Yuping, Yin Xiangli, Li Jingjie, Li Haiyue, Liu Jianfeng, Liu Yuanwei, Tian Gang

Abstract excerpt

As genetic inheritance is an inevitable risk factor in the development of coronary heart disease (CHD), it is critical to identify the polymorphisms of CHD risk. This study explored whether the NPAS4 polymorphisms are related to the CHD risk in the Chinese Han population. Five SNPs in NPAS4 were genotyped using Agena Mass ARRAY from 499 CHD and 500 controls. RT-PCR detected the NPAS4 expression levels in...

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PMID: 35532855
DOI: 10.1007/s12012-022-09735-9

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