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Article

Atypical hemolytic uremic syndrome induced by SARS-CoV2 infection in infants with EXOSC3 mutation.

Pediatric nephrology (Berlin, Germany) - 1 Nov 2022

Van Quekelberghe Chantal, Latta Kay, Kunzmann Steffen, Grohmann Maik, Hansen Matthias

Abstract excerpt

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by systemic thrombotic microangiopathy mainly in the kidneys and mostly due to genetic disorders leading to uncontrolled activation of the complement system. Severe complications of SARS-CoV2 infection are linked to microvascular injury and complement activation is suspected to play a role in the pathogenesis of endothelial cell...

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Identifiers

PMID: 35522339
DOI: 10.1007/s00467-022-05566-6
PMCID: PMC9072151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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